Diarrhoea and Associated Clinical Features in Different Pathotypes of Diarrheagenic E. coliIsolated in Children: A Case-Control Study in a Tertiary Care Hospital

Background: Acute gastroenteritis remains to be a major health problem in children causing high morbidity and mortalityIn India, diarrhoea is the third most common cause of death younger than 5 years age, with an estimation 300,000 deaths each year. Diarrheagenic Escherichia coli (DEC) being one important bacterial agents, present hospital-based study was done enlighten on occurrence different pathotypes clinical features associated DEC related diarrhoea. Methods:The case-control carried out SCB Medical College, Odisha from October 2014 September 2016 childhood cases (≤ 14 age). Stool samples were collected processed isolate causative agent by standard biochemical test, serotyping multiplex PCR. Results: 350 100 controls included study. The isolated significantly more control group (P value = 0.0205) isolation rate 7.4% cases. 12 (46.2%) 0-1 year age followed 1-5 i.e. 11 (42.3%) least 5-14 3 (11.5%). pathotype Enterotoxigenic E. (ETEC) Enteropathogenic E.coli (EPEC). Fever symptom diarrhoea; other two symptoms watery vomiting. Exclusive breastfeeding protective factor. Seasonal variation found among rainy season. Conclusion: Different commonly diarrhoea, correct identification various types along knowledge reduce mortality caused it.